海外

Postdoctoral Fellow : Houston, United States
Employer: University of Texas Medical School at Houston
Website: http://www.uthouston.edu/gsbs/faculty/faculty-directory/faculty-profiles.htm?id=1346099
Location: Houston, TX, United States
Type: Postdoctoral
Posted: March 18, 2012
Expires: May 16, 2012

job description

One NIH-funded postdoctoral position is available immediately in the laboratory of Dr. Wenzheng Zhang in the Department of Internal Medicine, University of Texas Medical School at Houston. The University of Texas Medical School at Houston offers outstanding benefits and dynamic research environment within the multi-institutional Texas Medical Center. We emphasize motivation and productive work in a collegial environment. Start date negotiable; Summer 2012 preferred. Position opens until filled.
The lab is mainly interested in defining the in vivo function of Dot1, a gene encoding a histone methyltransferase specific for histone H3 lysine 79, in maintaining Na+ and water homeostasis, blood pressure, and development of diabetic nephropathy and chronic kidney disease. (http://www.uthouston.edu/gsbs/faculty/faculty-directory/faculty-profiles.htm?id=1346099) Several transgenic mouse models including Dot1 conditional knockout mice have been recently developed in the lab by using the Cre-loxP system. AQP2:Cre-expressing mice are being used to inactivate Dot1 and its putative downstream targets in the renal collecting duct to reveal the underlying molecular mechanism.
The successful candidate will use a variety of techniques to characterize the molecular and pathological phenotype of these mouse models. The ideal applicant should be highly motivated individual and have a recent PhD or MD degree in pathology, biochemistry, molecular biology, cell biology or a related field. Previous experience in transgenic mice is preferred.
To apply, please send a current resume/CV and the names and contact information of three references to: Dr. Wenzheng Zhang, MSB 5.135, University of Texas HSC, 6431 Fannin St., Houston, Texas 77030, USA. E-mail: Wenzheng.zhang@uth.tmc.edu.
The University of Health Science Center at Houston is an EEO/AA Employer. M/F/D/V. This is a security sensitive position and thereby subject to Ed

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