Employer: Duke University Medical Center
Website: http://mgm.duke.edu/faculty/l...
Location: Durham, NC, USA
Type: Postdoctoral
Posted: June 23, 2011
Expires: August 15, 2011
Jobs by tag(s): ebv viral oncology b cells
 
job description

A postdoctoral position is available to study Epstein-Barr virus mediated B cell growth transformation in the laboratory of Dr. Micah Luftig on a NIH Training Grant at Duke University School of Medicine in the department of Molecular Genetics and Microbiology (http://mgm.duke.edu/faculty/luftig/).

The laboratory studies host innate tumor suppressor responses that negatively regulate EBV transformation. We have recently identified the host DNA damage response as a critical suppressor of EBV transformation (Nikitin, et al., Cell Host and Microbe, 2010, 8(6):510-522). We are currently investigating the viral latent proteins responsible for activating this response early after B cell infection and the mechanism by which the virus overcomes this response during B cell immortalization.

Our laboratory also maintains a vibrant ongoing collaboration with Prof. Bryan Cullen studying the* role of cellular miRNAs in EBV transformation.*

The successful candidate for this position will be a motivated and well-trained Ph.D. in cell biology, genetics, or a closely related field, preferably with a background in cancer cell signaling or EBV/herpesvirus biology. This candidate will be eager to work in a robust academic environment helping to train graduate students and undergraduates while making important fundamental contributions to the study of B cell lymphomagenesis and EBV biology.

Due to NIH fellowship requirements the successful applicant must be a US citizen or Legal Permanent Resident.

Applicants are invited to send their curriculum vitae, summary of past work, and contact information for three references to Dr. Micah Luftig. (E-mail: micah.luftig@duke.edu).

Duke University Medical Center is an Equal Opportunity/Affirmative Action Employer

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