Employer: National University of Singapore (NUS)
Website: http:///www.pharmacy.nus.edu....
Location: Singapore
Type: Postdoctoral
Posted: June 14, 2011
Expires: July 31, 2011
 
job description

A postdoctoral fellow position is available immediately in Dr. Victor Yu’s laboratory at National University of Singapore (NUS). The prime focus of the laboratory is to study the key signaling mechanisms operating in mitochondria responsible for regulating the cell death decisions in mammalian cells.

To facilitate a better understanding of the work being pursued in the laboratory, prospective applicants are urged to refer to the following recent papers published by the laboratory: (1). K.O. Tan et al., MAP-1 is a mitochondrial effector of Bax, (Track II), Proc. Natl. Acad. Sci. USA, 102: 14623-14688, 2005. (2). N.Y. Fu et al., Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria, (Track II), Proc. Natl. Acad. Sci. USA, 104: 10051-10056, 2007. (3) N.Y. Fu et al., Baxβ: a constitutively active human Bax isoform that is under tight regulatory control by the proteasomal degradation mechanism, Molecular Cell, 33: 15-29, 2009. (4) S.K. Sukumaran et al., A soluble form of the pilus protein FimA targets the VDAC-hexokinase complex at mitochondria to inhibit host cell apoptosis, Molecular Cell, 37: 768-783, 2010

Requirements:
Successful applicants are expected to have a strong background in molecular biology and biochemistry. Applicants with outstanding background in using in vivo (mouse) and/or in vitro systems for studying physiological process (e.g. cell death, cancer, neuro-degeneration, inflammation or ageing) regulated by mitochondria are invited to apply. Successful applicant should have a Ph.D. degree awarded by an internationally recognized institution within the last three years and should have a record of productivity supported by a record of publications in recognized peer-reviewed international journals.
Applicant should email his/her full curriculum vitae and contact information (email and phone number) of three individuals who would have first-hand knowledge of his/her ability in scientific research to:

Victor C. Yu, Ph.D.
Associate Professor
Department of Pharmacy
Faculty of Science
National University of Singapore
Email: phayuv@nus.edu.sg

Salary and benefits will be commensurable to educational qualifications and working experience. To ensure full consideration, all application materials should be presented in a single submission. Only short-listed candidates will be notified. Applications will be reviewed until the position is filled.

来源：未知